Autonomic Nervous System Dysfunction Impacts Pregnancy Course in Women with Heart Rate Variability Disorders

Abstract

The gestational period involves dynamic changes in the autonomic nervous system (ANS) as the body adapts to pregnancy. While generally considered adaptive, disturbances in ANS regulation can disrupt “mother-placenta-fetus” homeostasis, leading to complications. While previous research has primarily focused on the association of heart rate variability (HRV) with specific pregnancy complications, a comprehensive understanding of ANS dysfunction across the entire gestational period and its association with broader pregnancy outcomes remains understudied. This study aims to address this gap by investigating the impact of ANS dysfunction, diagnosed through cardiointervalography and HRV analysis, on the overall course of pregnancy.