Isolation and Identification of Certain Types of Skin Fungi and Their Ability to Produce Virulence Factors

Abstract

The current study examined the isolation and diagnosis of dermatological fungi from patients reviewed for the dermatology consultation of Tikrit Teaching Hospital and diagnosed by dermatologists and for the period from 1/4/2022 to 15/10/2023 and the detection of the ability of some of the isolated dermatological fungi to produce some of the important virulent factors for incidence electrosporum. Epidermatophyton, where Trichophyton was the most frequent sex and 65 isolated spots belonging to several species, the sex Microsoft recorded 13 isolations while the sex Epidermatophyton recorded two isolations.

Five clinical forms emerged: Tinea Corporis, Tinea capitis, Tinea Pedis, Tinea Manus and Tinea Faciei, with the highest Tinea Corporis infection rate at 32.5%, while the lowest Tinea Faciei infection rate at 8.75%.

Through the study, the susceptibility of isolated fungi to the production of hemolysin and phospholipase enzymes was identified. The most productive Dermatophyte of the phospholipase enzyme are subordinate to the fungal species T.rubrum, T.mentagrophytes, T.tonsurans and 21 isolates. 17, 8 each, while M.canis and the lowest number of 5 isolates are recorded, M.gypsum and Epidermatophyton flocosum have no susceptibility to the production of phospholipes. As the results of this study have shown, all isolated Dermatophyte have the potential to produce hemolysin enzyme and the isotropic skin fungus events. The production of hemolysin by fungi plays an important role in the balance between the host's cellular immunity and the susceptibility of mushrooms to reduce the host's immune response.

Based on the foregoing, the study aims to: Isolate and diagnose types of Dermatophyte causing skin injuries as well Detect their susceptibility to the production of certain virulence agents in vitro.