Synthesis and Characterization and Biological Study of Some Oxazepine Derivatives from 2-Acetylthiazole

Abstract

This study involved the preparation of different α-β unsaturated compounds by reacting 2-acetylthiazole with different aromatic benzaldehyde substituents (E1-E5) and reacting compounds (E1-E5) with 2-aminophenol. The minimal medium with 10% NaOH was then examined for the inhibitory activity against E. coli and Gram-positive Staphylococcus aureus using some spectroscopic methods. : H1-NMR, 13C-NMR, and TLC techniques were used to confirm the effectiveness of the prepared compounds.