Estimating of IL17, TNF Levels and Some Antioxidant Enzymes in Sexual Transmitted Virus Patients in Baghdad City

Sexually transmitted infections (STIs) are an important global public health problem. so this investigation was aimed to estimating of IL17, TNF levels and some antioxidant enzymes in sexual transmitted virus patients in Baghdad city. This study was conducted Between March 2024 and January 2025 in Al-Yarmuk Teaching Hospital, Baghdad, Iraq. 180 individuals are afflicted with sexually transmitted illnesses. The study comprised patients aged 18 to 55 who had or did not exhibit symptoms of a genital tract infection. The results showed the prevalence of human papillomavirus reaching 31(17.2%) and cytomegalovirus reaching 123(68.3%) in patients with sexually transmitted infections. MDA levels in serum of HPV patients (271.55 ± 18.19) CMV patients (229.52 ± 25.82) revealed a significant (P <0.05) rise in contrast with healthy participants (47.01± 13.26). GSH levels in serum of HPV patients (2.41 ± 1.04) CMV patients (2.75 ± 0.93) revealed a significant (P <0.05) reduced in contrast with healthy participants (13.95± 2.48). IL-17 levels in serum of HPV patients (291.35 ±21.62) CMV patients (205.41 ±14.66) revealed a significant (P <0.05) rise in contrast with healthy participants (83.19± 9.04). TNF-α levels in serum of HPV patients (296.41 ±22.85) CMV patients (341.74 ±31.67) revealed a significant (P <0.05) rise in contrast with healthy participants (64.15± 9.37). its concluded that the human papillomavirus (HPV) and cytomegalovirus (CMV) are sexually transmitted and directly affect oxidative stress in the body's cells, reducing antioxidant enzymes.