The Impact of Hypothyroidism in Some Reproductive Hormones in Women in Maysan Province

Background: Hypothyroidism is a common endocrine disorder, resulting from insufficient production of thyroid hormones. It is affect metabolism of sex steroids and ovarian function in women. Methods: This study was conducting on 88 women in reproductive age (20-35) years who reviewed Al-Sader Teaching Hospital and the Diabetes and Endocrine Center in Maysan  city  .Women divided in to four groups as the following: group A (Control group), group B( Infertility women), group C (Women with hypothyroidism) and group D (Women with hypothyroidism and infertility) . Thyroid and reproductive hormones measurements were done by the Chemiluminescent Automates Immunoassay System.  Results: The results showed: the values of TSH increased significantly (P<0.05) in the C (hypothyroidism women) and D(hypothyroidism and infertility women) groups, while T3 and T4 results show decreased significantly(P<0.05) in the C(hypothyroidism women) and D(hypothyroidism and infertility women) groups . The results showed that FSH values significant increase in the D(infertile women with hypothyroidism) group, LH values did not differ significantly among four groups ,while progesterone values showed significant decrease in the C(fertile women with hypothyroidism) and D(infertile women with hypothyroidism) groups , E2 values significant increase in the B (infertile women) and C(fertile women with hypothyroidism) groups and decrease in the D (infertile women with hypothyroidism) group in comparison with A (control)group.