Features of the Clinical Course of Coronary Artery Disease in Patients with Covid-19 Depending on the Presence of Metabolic Syndrome

Abstract

This analysis will not only allow for a more precise understanding of the development of metabolic syndrome and the progression of coronary artery disease, but it will also help identify the impact of 2019-nCoV infection on heart damage.

Objective: To study the pathogenetic significance of COVID-19 in the progression of metabolic syndrome and destabilization of coronary artery disease (CAD).

Object of the Study: 147 patients with CAD against the background of metabolic syndrome who received treatment in a COVID specialized center.

Subject of the Study: Blood and blood serum of patients with CAD for the quantitative determination of key biochemical parameters (lipid profile).

Conclusions: A notable feature of the clinical course of CAD with metabolic syndrome in patients with COVID-19 is the frequent occurrence of multiple anginal attacks, episodes of tachycardia, rhythm variability impairments such as ventricular extrasystoles, complete left bundle branch block, ST-segment elevation on the ECG, enhanced T-wave inversion, and progression of unstable angina. Patients with CAD and metabolic syndrome infected with COVID-19 demonstrated an increase in the atherogenic index, elevated mean triglyceride levels, and decreased mean serum HDL concentrations compared to optimal parameters and values in the group of patients without metabolic syndrome.