The Effect of Vitamin a on Melanin Production: A Review

Abstract

A fat-soluble micronutrient, vitamin A is essential for the development of strong, healthy skin and hair. However, there are negative effects from both too little and too much of this vitamin. The two primary active metabolites of vitamin A are retinol and retinoic acid. Hair follicle stem cells are regulated by retinoic acid, which also affects melanocyte stem cells as well as the wound healing, and hair cycle activity. Additionally, melanocyte differentiation and proliferation are influenced by retinoic acid in a temporally and dose-dependent way. According to these studies, maintaining healthy skin and hair requires consuming enough vitamin A, which can be harmful if taken in excess or insufficiently.