Preparation, Characterization, Biological Activity Evaluation, and Liquid Crystallography Study of New Diazepine Derivatives

This research included the use of solid basic catalysts as a catalyst, where the crystalline surface was confirmed using scanning electron microscopy, where it was introduced into the reaction of prepared chalcones, which are intermediate compounds in the preparation of heterogeneous rings, with 2-aminoaniline to prepare heterogeneous heptad rings derived from diazepine, where the correctness of the prepared structures was confirmed using infrared spectra and proton and carbon nuclear magnetic resonance spectra. Its biological activity was also tested against two types of Gram-positive bacteria, Staphylococcus epidermidis and Gram-negative Klebsiella pneumoniae. The crystalline phases of some of the prepared compounds were studied, where some of them gave crystalline phases.