Therapeutic Effects of the Pharmaceutical Product – Phenomenon at Experimental Liver Cirrhosis

Abstract

Article provides results of investigation carried out on lad. Rats with  CCl4-induced liver cirrhosis and treated with differend   drugs (Phenomenon and  S-ademethioninein).  Treatment efficacy was evaluated according to the biochemical parameters: Aspartate aminotransferase (AST), Alanine aminotransferase (ALT), Sodium phosphatase (ALP), total bilirubin (TBIL), Cholesterol, serum Creatinine (CREA), Blood glucose, superoxide dismutase (SOD) and morphology of liver tissue. Investigations  showed  that the better therapeutic effects were detected at treatment with phenomenon, especially at combination phenomenon+honey compared to the data of the animals treated with S-ademethionine. Conclusion: phenomenon reveals antioxidant, membrane-stabilizing, hepatoprotective properties, decreases lipid peroxidation, inhibits damage of hepatocytes, and improves liver functions in CCl4 induced liver cirrhosis in lab rats.